Patent · US Active

Truncated variant of the mammalian target for rapamycin (MTOR) protein

US8669347B2 · kind B2 · utility

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Key dates

Filing dateMay 1, 2008
Grant dateMar 11, 2014
Priority date
Expiry dateDec 4, 2029

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2440/14
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The invention relates to mTORbeta, a splice form of mTOR, nucleic acids encoding mTOR beta, and antibodies against mTOR beta. The invention also relates to methods of producing mTOR beta and methods of screening for an agent that modulates mTOR beta expression and/or activity. The invention further relates to a method of treating a disease associated with aberrant expression of mTOR beta by administration of an agent that alters mTOR activity and/or expression.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.