Methods of converting amorphous drug substance into crystalline form
US8669360B2 · kind B2 · utility
3Cited by
302References
9Claims
0Family size
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Key dates
| Filing date | Sep 23, 2011 |
| Grant date | Mar 11, 2014 |
| Priority date | — |
| Expiry date | Dec 13, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for converting an amorphous drug, such as everolimus, or other macrolide immunosuppressive drug, into a crystalline form. The method utilizes a slurry of the drug in organic liquid phase and ages the slurry to achieve the conversion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.