Bioanalytical instrumentation using a light source subsystem
US8673218B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 1, 2012 |
| Grant date | Mar 18, 2014 |
| Priority date | — |
| Expiry date | Jul 3, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6484
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a light source for irradiating molecules present in a detection volume with one or more selected wavelengths of light and directing the fluorescence, absorbance, transmittance, scattering onto one or more detectors. Molecular interactions with the light allow for the identification and quantitation of participating chemical moieties in reactions utilizing physical or chemical tags, most typically fluorescent and chromophore labels. The invention can also use the light source to separately and simultaneously irradiate a plurality of capillaries or other flow confining structures with one or more selected wavelengths of light and separately and simultaneously detect fluorescence produced within the capillaries or other flow confining structures. In various embodiments, the flow confining structures can allow separation or transportation of molecules and include capillary, micro bore and milli bore flow systems. The capillaries are used to separate molecules that are chemically tagged with appropriate fluorescent or chromophore groups.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.