Sphingoid polyalkylamine conjugates for vaccination
US8673285B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 17, 2004 |
| Grant date | Mar 18, 2014 |
| Priority date | — |
| Expiry date | Feb 18, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/55561
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns the use of a sphingoid-polyalkylamine conjugate as a capturing agent of biologically active molecules, such as antigens. In a particular embodiment, the spinogid-polyalkylamines are used for the preparation of pharmaceutical composition for modulating the immune response of a subject. Other aspects of the invention concern methods for modulating the immune response of a subject by the use of the conjugate, complexes comprising, the sphingoid-polyalkylamine conjugate in combination with a biologically active molecule capable of modulating an immune response of a subject, compositions comprising the conjugate as well as kits making use of said conjugate. A preferred conjugate according to the invention is N palmitoyl D-erythro sphingosyl 1 carbamoyl spermine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.