Patent · US Active

Diagnosis and monitoring of renal failure using peptide biomarkers

US8673574B2 · kind B2 · utility

0Cited by

2References

30Claims

0Family size

Assignee

PxBioSciences LLC · US

Inventors

Harald Tammen · Hannover, DE
Leif E. Honda · Rye, US
Michael Jürgens · Schwetzingen, DE
Andrew Peck · Ridgewood, US

Key dates

Filing date	Aug 20, 2009
Grant date	Mar 18, 2014
Priority date	—
Expiry date	Oct 19, 2031

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/52
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Methods for the determination of renal failure, especially chronic renal failure and acute kidney injury, by measurement of peptide or protein biomarkers are described. The methods are useful to determine stages of renal failure, especially the early stages such as stage 1, 2, and 3 of chronic renal failure and stages R and I of acute kidney injury. Furthermore there are described peptides and test kits used in the invention. The described methods are intended to replace or complement the measurement of creatinine and/or cystatin C and/or NGAL for diagnosis of renal failure.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.