Patent · US Active

Methods of identifying antagonists of the hTAS2R46 bitter taste receptor

US8673578B2 · kind B2 · utility

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14Claims

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Assignee

Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke · DE

Inventors

Giovanni Appendino · Michendorf, DE
Maik Behrens · Michendorf, DE
Anne Brockhoff · Delitzsch, DE
Wolfgang Meyerhof · Norderstedt, DE

Key dates

Filing date	Oct 27, 2010
Grant date	Mar 18, 2014
Priority date	—
Expiry date	Oct 27, 2030

Classification

Technology area (CPC G)Physics
CPC primaryG01N2500/04
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to antagonists and agonists of the human bitter-taste receptors hTAS2R40, hTAS2R43, hTAS2R44, hTAS2R46, and hTAS2R47. The invention also relates to methods for identifying further molecules that suppress or enhance bitter taste transduction or bitter taste response mediated by hTAS2R40, hTAS2R43, hTAS2R44, hTAS2R46, and/or hTAS2R47 and uses thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.