Patent · US Active

Monoclonal antibodies that bind to HGM-CSF and medical compositions comprising same

US8679502B2 · kind B2 · utility

0Cited by

11References

64Claims

0Family size

Assignees

EVEC INC. · JP
Boehringer Ingelheim International GmbH · DE

Inventors

Kenzo Takada · Ube, JP
Kantou Nakajima · Sapporo, JP
Barbara Kistler · Pfungstadt, DE
John Park · Warthausen, DE

Key dates

Filing date	Nov 12, 2008
Grant date	Mar 25, 2014
Priority date	—
Expiry date	Nov 23, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are anti-hGM-CSF monoclonal antibodies and antigen-binding fragments of such antibodies, with improved neutralizing capacity to hGM-CSF activity. Pharmaceutical compositions comprising such an antibody or antigen-binding fragment are also provided. The present invention is useful for the treatment of various diseases that are associated with aberrant expression of hGM-CSF.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.