Oncolytic viruses and methods for treating neoplastic disorders

US8679509B2 · kind B2 · utility

Assignee

• The Governors of the University of Alberta · CA

Inventors

• David H. Evans · Cambridge, US
• Don B. Gammon · Worcester, US

Key dates

• Filing date: Jul 9, 2010
• Grant date: Mar 25, 2014
• Expiry date: Jul 9, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2710/24162
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure provides mutant ribonucleotide reductase strains of poxviruses including for example vaccinia viruses. The disclosure also provides methods and for the use of these mutant ribonucleotide reductase strains of vaccinia viruses in oncolytic virotherapy.