PCR methods for characterizing the 5′ untranslated region of the FMR1 and FMR2 genes
US8679757B2 · kind B2 · utility
4Cited by
13References
106Claims
0Family size
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Key dates
| Filing date | Feb 16, 2010 |
| Grant date | Mar 25, 2014 |
| Priority date | — |
| Expiry date | Jul 16, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6858
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This disclosure relates to methods of determining the presence and position of AGG or interruptor elements within a trinucleotide (for example, CGG) repeat region, and to methods of determining the number of repeats present in this region, by amplifying a set of products with a set of primers of which at least one comprises a portion of the CGG repeat region, and resolving the products to produce a representation of product size and abundance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.