Patent · US Active

PCR methods for characterizing the 5′ untranslated region of the FMR1 and FMR2 genes

US8679757B2 · kind B2 · utility

4Cited by
13References
106Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 16, 2010
Grant dateMar 25, 2014
Priority date
Expiry dateJul 16, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6858
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

This disclosure relates to methods of determining the presence and position of AGG or interruptor elements within a trinucleotide (for example, CGG) repeat region, and to methods of determining the number of repeats present in this region, by amplifying a set of products with a set of primers of which at least one comprises a portion of the CGG repeat region, and resolving the products to produce a representation of product size and abundance.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.