Serum bactericidal assay for N. meningitidis specific antisera
US8679770B2 · kind B2 · utility
6Cited by
0References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 5, 2005 |
| Grant date | Mar 25, 2014 |
| Priority date | — |
| Expiry date | Dec 17, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2469/20
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the field of Serum Bactericidal Activity (SBA) assays for Gram negative bacteria, in particular N. meningitidis. The SBA assay is the most important method for measuring functional activity of serum antibodies against meningococcus. In order to determine whether a subject or a population is seropositive against invasive meningococcus the SBA test should ideally be both sensitive and specific. The inventors have found the standard N. meningitidis serotype A and W SBAs can be significantly improved in this regard.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.