Recombinant factor X with no glycosylation and method for preparing the same
US8679783B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Feb 24, 2012 |
| Grant date | Mar 25, 2014 |
| Priority date | — |
| Expiry date | Apr 16, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essential for glycosylation in FX to thereby allow for expression of a recombinant FX with no glycosylation, and the recombinant FX with no glycosylation obtained by said method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.