Production of acid and solvent in microorganisms

US8679799B2 · kind B2 · utility

Assignee

• SUDZUCKER AKTIENGESELLSCHAFT MANNHEIM/OCHSENFURT · DE

Inventors

• Wolfgang Wach · Worms, DE
• Karsten Harms · Worms, DE
• Michael Klingeberg · Bad Kötzting, DE
• Peter Duerre · Ulm, DE
• Niklas Nold · Biberach, DE
• Bettina Schiel · Ulm, DE

Key dates

• Filing date: Dec 15, 2009
• Grant date: Mar 25, 2014
• Expiry date: Jun 15, 2030

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02E50/10
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a method and means for the bioengineered fermentative production of solvents, in particular of butanol, acetone and ethanol, and of short-chained carboxylic acids such as acetic acid and butyric acid, in particular in host cells of the species Clostridium. The invention provides new methods and means for regulating the expression of the enzyme activities involved in acid production and or solvent production of the host cell.