Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation
US8679810B2 · kind B2 · utility
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1References
13Claims
0Family size
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Key dates
| Filing date | Feb 12, 2007 |
| Grant date | Mar 25, 2014 |
| Priority date | — |
| Expiry date | Jul 30, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides an isolated and substantially purified recombinant human arginase having sufficiently high enzymatic activity and stability to maintain Adequate Arginine Depletion in a patient. The present invention also provides a pharmaceutical composition comprising the modified invention enzyme and method for treatment of diseases using the pharmaceutical composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.