Selectively targeted antimicrobial peptides and the use thereof

US8680058B2 · kind B2 · utility

Assignees

• The Regents of the University of California · US
• C3 Jian, LLC · US

Inventors

• Randal H. Eckert · Redondo Beach, US
• Daniel K. Yarbrough · Los Angeles, US
• Wenyuan Shi · Los Angeles, US
• Maxwell H. Anderson · Sequim, US
• Fengxia Qi · Laguna Niguel, US
• Jian He · Blue Bell, US
• Ian H. McHardy · Santa Monica, US

Key dates

• Filing date: Nov 2, 2010
• Grant date: Mar 25, 2014
• Expiry date: Nov 2, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/01
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to targeting peptides capable of specifically binding to microbial organisms (e.g., P. aeruginosa or S. mutans), antimicrobial peptides having antimicrobial activities, and specifically/selectively targeted antimicrobial peptides (STAMPs). In addition, the present invention provides methods of selectively killing or inhibiting microbial organisms by using the peptides or compositions provided by the present invention.