Macrocyclic amides, pharmaceutical compositions, preparation methods and uses thereof
US8680087B2 · kind B2 · utility
1Cited by
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10Claims
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Key dates
| Filing date | Nov 30, 2010 |
| Grant date | Mar 25, 2014 |
| Priority date | — |
| Expiry date | Nov 30, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Macrocyclic amide WH-21091 with antibacterial and antitumor activities, its analogs, preparation methods and uses thereof. The said macrocyclic amides are prepared by microbes of Xenorhabdus and Photorhabdus, or they can be prepared by other living beings through transgenic techniques. The compositions of the said macrocyclic amide and its analogs can be used as drugs and/or agricultural chemicals for treatment of microbial infections, especially for treatment of infectious diseases of Staphylococcus aureus with drug resistance. The said compositions can also be used as drugs for treatment of cancers of human beings or animals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.