Processes of enantioselectively forming an aminoxy compound and an 1,2-oxazine compound
US8680335B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 18, 2010 |
| Grant date | Mar 25, 2014 |
| Priority date | — |
| Expiry date | May 3, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C239/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed is a process of enantioselectively forming an aminoxy compound of Formula (3)In formula (3) R1 is one of an aliphatic group and an alicyclic group. R2 is one of hydrogen, an aliphatic group, an alicyclic group, an aromatic group, an arylaliphatic group and an arylalicyclic group. R3 is one of hydrogen, halogen, hydroxyl, and an aliphatic group with a main chain having 1 to about 10 carbon atoms. The respective aliphatic, alicyclic, aromatic, arylaliphatic or arylalicyclic groups of R1, R2, and R3 comprise 0 to about 3 heteroatoms independently selected from the group consisting of N, O, S, Se and Si. The process includes contacting a carbonyl compound of Formula (1)and a nitroso compound of Formula (2)in the presence of a chiral catalyst. The chiral catalyst is a compound of Formula (IX)
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.