Chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer
US8685398B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Jun 15, 2010 |
| Grant date | Apr 1, 2014 |
| Priority date | — |
| Expiry date | Jun 15, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel polypeptides comprising a chemokine-binding peptide and an Fc fragment are disclosed. The polypeptides are capable of binding to certain chemokines so as to modulate their activity. These polypeptides can be used to modulate in vivo chemokine-dependent processes such as inflammation and autoimmunity, and to treat associated conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.