Cyclohexylamines

US8685418B2 · kind B2 · utility

Assignee

• ENDO PHARMACEUTICALS INC. · US

Inventors

• Scott K. Thompson · Phoenixville, US
• Roger Smith · Madison, US
• Sandeep Gupta · Plainsboro, US
• Tony Priestley · West Chester, US
• Nicholas James Laping · Malvern, US
• Ashis Saha · Stow, US
• Sonali Rudra · Sherghati, IN

Key dates

• Filing date: Oct 24, 2012
• Grant date: Apr 1, 2014
• Expiry date: Oct 24, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present application provides novel compounds and methods for preparing and using these compounds. These compounds are useful in treating pain, itch, overactive bladder and/or interstitial cystitis in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) and a TRPV1 receptor activator. In one embodiment, the TRPV1 receptor activator is lidocaine.