Patent · US Active

Medical methods and agents for use therein

US8685640B2 · kind B2 · utility

0Cited by

1References

14Claims

0Family size

Assignee

ALLIGATOR BIOSCIENCE AB · SE

Inventors

Thomas Tötterman · Uppsala, SE
Linda Sandin · Uppsala, SE
Angelica Loskog · Uppsala, SE
Sara Mangsbo · Uppsala, SE
Peter Ellmark · Lund, SE

Key dates

Filing date	Nov 17, 2010
Grant date	Apr 1, 2014
Priority date	—
Expiry date	Nov 17, 2030

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/52
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides an immunomodulatory agent for use in the local treatment of tumors, wherein the treatment comprises patient-specific optimization of the dose of the immunomodulatory agent to identify the maximum therapeutic dose that does not induce an increase in the number of local regulatory T cells (Treg cells) in the patient The invention further provides methods for the local treatment of tumors as well as methods for optimising treatments for the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.