Patent · US Active

Microorganism for the production of succinic acid

US8685704B2 · kind B2 · utility

1Cited by

4References

6Claims

0Family size

Assignee

ORGANOBALANCE GMBH · DE

Inventors

Christine Lang · Berlin, DE
Markus Veen · Berlin, DE
Mewes Böttner · Berlin, DE
Andreas Raab · Neuler, DE

Key dates

Filing date	Apr 16, 2008
Grant date	Apr 1, 2014
Priority date	—
Expiry date	Mar 16, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N9/88
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to an isolated genetically modified microorganism in which the gene IDH1 and at least one of the genes SDH2 and DIC1 are under the control of a first promoter that is repressed to a growth culture medium by means of a cultivation additive and is active in the absence of the cultivation additive. The genes that are part of the group comprising “PYC1, ACS1, CIT1, ACO1, ICL1, MSL1, and CIT2, optionally also MDH3” are constitutively active. The invention further relates to uses of such a microorganism, especially for producing succinic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.