Ex vivo flow cytometry method and device
US8685752B2 · kind B2 · utility
5Cited by
50References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 2, 2007 |
| Grant date | Apr 1, 2014 |
| Priority date | — |
| Expiry date | Oct 3, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2458/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a method for diagnosing a disease state mediated by pathogenic cells. The method comprises the steps of combining with an ex vivo patient sample a composition comprising a conjugate or complex of the general formula Ab-X, wherein the group Ab comprises a ligand that binds to the pathogenic cells and the group X comprises an imaging agent, and detecting the pathogenic cells that express a receptor for the ligand using flow cytometry.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.