Patent · US Active

Compositions and methods for inhibiting sphingosine kinase

US8686046B2 · kind B2 · utility

1Cited by

5References

20Claims

0Family size

Assignee

University of Virginia Patent Foundation · US

Inventors

Kevin R. Lynch · Charlottesville, US
Timothy L. Macdonald · Charlottesville, US
Yugesh Kharel · Charlottesville, US
Thomas P. Mathews · Gainesville, US
Brian R. Wamhoff · Charlottesville, US

Key dates

Filing date	Oct 2, 2010
Grant date	Apr 1, 2014
Priority date	—
Expiry date	May 31, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D409/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Amidine analogs that can inhibit the activity of sphingosine kinase 1 and sphingosine kinase 2 (SphK1 & SphK2) are provided. The compounds can prevent angiogenesis in tumor cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.