Therapeutic pro-apoptotic BH3-like molecules and methods for generating and/or selecting the same
US8686110B2 · kind B2 · utility
1Cited by
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13Claims
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Key dates
| Filing date | Jun 23, 2006 |
| Grant date | Apr 1, 2014 |
| Priority date | — |
| Expiry date | Aug 8, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitating apoptosis of a target cell or cell population such as cancer cells. The present invention further provides methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.