Molecular conjugate
US8686122B2 · kind B2 · utility
7Cited by
45References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 14, 2010 |
| Grant date | Apr 1, 2014 |
| Priority date | — |
| Expiry date | Mar 13, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/535
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method is disclosed for making a conjugate of two molecules using a hydrazide thiol linker. In a particular working embodiment, an Fc-specific antibody-enzyme conjugate is made using the method and demonstrated to provide exceptional staining sensitivity and specificity in immunohistochemical and in situ hybridization assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.