LPA receptor agonists and antagonists
US8686177B2 · kind B2 · utility
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Key dates
| Filing date | Mar 3, 2009 |
| Grant date | Apr 1, 2014 |
| Priority date | — |
| Expiry date | Mar 3, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/173
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are compounds according to formula (I) as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including treating cancer, producing radioprotection and/or radiomitigation, enhancing cell proliferation, treating a wound, treating apoptosis or preserving or restoring function in a cell, tissue, or organ, culturing cells, preserving organ or tissue function, and treating a dermato logical condition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.