Patent · US Active

High growth reassortant influenza A virus

US8691238B2 · kind B2 · utility

0Cited by

0References

17Claims

0Family size

Assignee

Baxter Healthcare SA · CH

Inventors

Thomas Muster · Wien, AT
Markus Wolschek · Wien, AT
Andrej Egorov · Wien, AT
Elisabeth Roethl · Wien, AT
Julia Romanova · Wien, AT
Michael Bergmann · Klosterneuburg, AT

Key dates

Filing date	Dec 18, 2009
Grant date	Apr 8, 2014
Priority date	—
Expiry date	Feb 16, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2760/16151
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a high growth reassortant influenza A virus having at least two gene segments of seasonal or pandemic strain origin, a PB1 gene segment of A/Texas/1/77 strain origin and a PA gene segment of A/Puerto Rico/8/34 (H1N1) origin coding for a PA protein comprising at least one amino acid modification at any one of positions 10, 275, 682, according to SEQ ID No. 1. Further provided are vaccine formulations comprising the reassortant influenza A virus of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.