Ingestible formulations for transient, noninvasive reduction of gastric volume
US8691271B2 · kind B2 · utility
14Cited by
12References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 25, 2008 |
| Grant date | Apr 8, 2014 |
| Priority date | — |
| Expiry date | Oct 25, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/546
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are ingestible polymeric formulations and oral dosage forms for the reduction of gastric volume in the treatment of overweight and obese patients. The formulation includes an acid-sensitive, gelatin coating over a dehydrated hydrophilic polymer. When ingested, the acid-sensitive coating is quickly dissolved by gastric secretions and the hydrophilic polymer is exposed to the aqueous environment of the gastric milieu. The polymer absorbs water and expands to the point that will not allow the polymer to pass beyond the pyloric valve, and the expanded polymer is therefore trapped in the stomach.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.