Patent · US Active

Extracellular matrix-derived gels and related methods

US8691276B2 · kind B2 · utility

29Cited by

43References

18Claims

0Family size

Assignee

University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

Stephen F. Badylak · Lafayette, US
Donald Freytes · Pittsburgh, US

Key dates

Filing date	Nov 26, 2012
Grant date	Apr 8, 2014
Priority date	—
Expiry date	Nov 26, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61L2420/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are methods for preparing gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth scaffolds. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.