Flexible carbohydrate-bearing polymer
US8691517B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 6, 2006 |
| Grant date | Apr 8, 2014 |
| Priority date | — |
| Expiry date | Oct 12, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/66
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A sensor for the detection or measurement of a carbohydrate analyte in fluid comprises components of a competitive binding assay the readout of which is a detectable or measurable optical signal retained by a material that permits diffusion of the analyte but not the assay components, the assay components comprising: a carbohydrate binding molecule labelled with one of a proximity based signal generating/modulating moiety pair; and a carbohydrate analogue capable of competing with the analyte for binding to the carbohydrate binding molecule, the carbohydrate analogue being a flexible water-soluble polymer comprising: polymerized or co-polymerised residues of monomer units, the monomer unit residues bearing pendant carbohydrate or carbohydrate mimetic moieties and pendant moieties which are the other of the proximity based signal generating/modulating moiety pair.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.