Nanofibrous scaffold comprising immobilized cells
US8691543B2 · kind B2 · utility
33Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 26, 2010 |
| Grant date | Apr 8, 2014 |
| Priority date | — |
| Expiry date | May 13, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/30
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The invention is directed to a device and method to prevent migration of Human Mesenchymal Stem Cells (hMSCs) from a delivery site while allowing communication between the stem cells and native cardiomyocytes. The device is characterized by scaffold pore size, fiber diameter and biomaterial selection. The invention includes a two part polyurethane scaffold that prevents migration of stem cells, allows gap junction formation through pores and is packaged for minimally invasive delivery.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.