Inhibitors of NF-κB activity
US8691764B2 · kind B2 · utility
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1References
56Claims
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Key dates
| Filing date | Mar 28, 2008 |
| Grant date | Apr 8, 2014 |
| Priority date | — |
| Expiry date | Jul 12, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for inhibiting NF-κB activity in a subject, the method comprising providing an agent capable of inducing expression of annexin 1, whereby said agent induces expression of annexin 1 and whereby said induced expression of annexin 1 inhibits NF-κB activity. Also provided are annexin 1 mimetics capable of binding to NF-κB and pharmaceutical compositions of such inducing and mimetic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.