Patent · US Active

Substituted benzoazepines as toll-like receptor modulators

US8691809B2 · kind B2 · utility

8Cited by

2References

17Claims

0Family size

Assignees

VentiRx Pharmaceuticals, Inc. · US
Array BioPharma, Inc. · US

Inventors

James Jeffry Howbert · Bellevue, US
Gregory Dietsch · Snohomish, US
Robert Hershberg · Seattle, US
Laurence E. Burgess · Boulder, US
Joseph P. Lyssikatos · South San Francisco, US
Brad Newhouse · Boulder, US
Hong Yang · Foster City, US

Key dates

Filing date	Aug 18, 2010
Grant date	Apr 8, 2014
Priority date	—
Expiry date	Nov 24, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D405/10
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.