Agents useful for reducing amyloid precursor protein and treating dementia and methods of use thereof
US8691864B2 · kind B2 · utility
12Cited by
11References
25Claims
0Family size
Inventors
Key dates
| Filing date | Jul 26, 2012 |
| Grant date | Apr 8, 2014 |
| Priority date | — |
| Expiry date | Jul 26, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds and methods of administering compounds to a subject that can reduce βAPP production and that is not toxic in a wide range of dosages. The present invention also provides non-carbamate compounds and methods of administering such compounds to a subject that can reduce βAPP production and that is not toxic in a wide range of dosages. It has been discovered that either the racemic or enantiomerically pure non-carbamate compounds can be used to decrease βAPP production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.