Antimicrobial filled capsules in an ultrasound field for treatment of dental biofilm
US8696353B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 9, 2008 |
| Grant date | Apr 15, 2014 |
| Priority date | — |
| Expiry date | Jan 3, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/82
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An appliance and corresponding method for delivering antimicrobial agents to the vicinity of dental biofilm and for killing bacteria therein includes a system (18, 20, 24) for delivering polymeric capsules containing gas bubbles and an antimicrobial agent. A source of ultrasonic energy (18) is provided for moving the capsules toward the biofilm, the ultrasonic energy having sufficient intensity for thereafter bursting the capsules, in the vicinity of the biofilm, releasing the gas bubbles and the agent. The gas bubbles vibrate within the ultrasound field, disrupting the biofilm, so that the released agent can act effectively against the bacteria in the disrupted biofilm.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.