Amyloid β fibrillogenesis-inhibiting peptide
US8697651B2 · kind B2 · utility
0Cited by
3References
19Claims
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Inventor
Key dates
| Filing date | Dec 16, 2011 |
| Grant date | Apr 15, 2014 |
| Priority date | — |
| Expiry date | Feb 15, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2821
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a peptide which functions as a mimic peptide of an amyloid β peptide and is capable of inhibiting the fibrillogenesis of an amyloid β peptide. The present invention relates to an 8- to 30-amino acid residue peptide comprising an amino acid sequence represented by the following formula (I): X1-Asp-X2-X3-X4-Pro-X5-X6 (SEQ ID NO: 28) (I), wherein X1 represents a branched chain amino acid, and X2, X3, X4, X5, and X6 are the same or different and each represents an α-amino acid, and to a pharmaceutical composition and an amyloid β fibrillogenesis inhibitor comprising the peptide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.