Treating diseases mediated by blockade of the epithelial sodium channel with pyrazine-2-carboxamide derivatives
US8697687B2 · kind B2 · utility
1Cited by
8References
3Claims
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Key dates
| Filing date | Sep 13, 2012 |
| Grant date | Apr 15, 2014 |
| Priority date | — |
| Expiry date | Sep 13, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of Formula Iin free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.