Pyrrolo [3,2-c] pyridine-4-one 2-indolinone protein kinase inhibitors
US8697692B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Aug 2, 2011 |
| Grant date | Apr 15, 2014 |
| Priority date | — |
| Expiry date | Dec 22, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to pyrrolo[3,2-c]pyridine-4-one 2-indolinone compounds of Formula (I) and their pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8 X, Y and have the meaning cited in the specification. Also disclosed are the pharmaceutical compositions containing the foregoing compounds, methods for the preparation and pharmaceutical use thereof, particularly as protein kinase inhibitors. Formula (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.