Pharmaceutical compounds
US8697693B2 · kind B2 · utility
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2References
18Claims
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Inventors
Key dates
| Filing date | Jul 19, 2012 |
| Grant date | Apr 15, 2014 |
| Priority date | — |
| Expiry date | Jul 19, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Thienopyrimidines of formula (Ia) or (Ib):wherein R1-R3 have any of the values described herein, and the pharmaceutically acceptable salt thereof have activity as inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behavior associated with PI3 kinase, in particular the p110 delta subtype, such as immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine disorders and neurological disorders. Processes for synthesizing the compounds are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.