Substituted phenylether-thienopyridone compounds with antibacterial activity
US8697720B2 · kind B2 · utility
1Cited by
6References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 11, 2007 |
| Grant date | Apr 15, 2014 |
| Priority date | — |
| Expiry date | Jun 7, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel bicyclic heteroaromatic compounds are provided that are inhibitors of bacterial methionyl tRNA synthetase (MetRS). Compounds of the invention generally have a left hand side phenylether constituent and a right hand side thienopyridone constituent. Also disclosed are methods for their preparation and their use in therapy as antibacterial agents, particularly as anti-Clostridium difficile agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.