5-lipoxygenase activating protein (FLAP) inhibitor
US8697730B2 · kind B2 · utility
1Cited by
50References
15Claims
0Family size
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Key dates
| Filing date | Oct 24, 2008 |
| Grant date | Apr 15, 2014 |
| Priority date | — |
| Expiry date | Sep 18, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are methods for the synthesis of 3-[5-(pyridin-2-ylmethoxy)-3-(2-methyl-2-propylthio)-1-[4-(2-methoxypyridin-5-yl)benzyl]-indol-2-yl]-2,2-dimethyl-propionic acid, pharmaceutically acceptable salts, pharmaceutically acceptable solvates thereof. Also described are pharmaceutical compositions suitable for oral administration to a mammal that include, as well as methods of using such oral pharmaceutical compositions for treating respiratory conditions or diseases, as well as other leukotriene-dependent or leukotriene mediated conditions or diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.