Patent · US Active

Substrate for Rpn 11 enzymatic activity

US8697837B2 · kind B2 · utility

0Cited by

1References

16Claims

0Family size

Assignee

Onyx Therapeutics, Inc. · US

Inventors

Francesco Parlati · San Francisco, US
Monette Aujay · San Francisco, US
Mark K. Bennett · Moraga, US

Key dates

Filing date	Jul 20, 2009
Grant date	Apr 15, 2014
Priority date	—
Expiry date	Mar 2, 2032

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/573
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present application provides peptides that serve as substrates for proteasome enzymatic activity, e.g., the enzymatic activity of Rpn11, a metalloprotease of the 19S regulatory particle. The present application also provides methods and compositions employing the peptide substrates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.