Patent · US Active

Modified macromolecule

US8703116B2 · kind B2 · utility

2Cited by

5References

12Claims

0Family size

Assignee

Starpharma Pty Ltd. · AU

Inventors

Benjamin James Boyd · Melbourne, AU
Lisa Michelle Kaminskas · Melbourne, AU
Christopher John Hamilton Porter · Melbourne, AU
Peter Karellas · Morgan, AU
Guy Krippner · Melbourne, AU
Pasquale Razzino · Parramatta, AU
Brian Devlin Kelly · Melbourne, AU
Zemin Wu · Melbourne, AU
Sue Pallich · Melbourne, AU

Key dates

Filing date	Dec 21, 2012
Grant date	Apr 22, 2014
Priority date	—
Expiry date	Dec 21, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08G83/003
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a macromolecule having a controlled terminal group stoichiometry, the macromolecule including a surface layer, at least one subsurface layer and at least two terminal groups including: a first terminal group which is a residue of a pharmaceutically active agent, a derivative thereof or precursor therefor; and a second terminal group selected to modify the pharmacokinetics of the pharmaceutically active agent and/or macromolecule, wherein terminal group stoichiometry refers to the number and type of terminal groups.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.