Patent · US Active

Method for obtaining biologically active recombinant human G-CSF

US8703123B2 · kind B2 · utility

4Cited by

1References

17Claims

0Family size

Assignee

BIOGENERIX GMBH · DE

Inventors

Walter Hinderer · Rodgau, DE
Christian Scheckermann · Ehrenkirchen, DE

Key dates

Filing date	Mar 17, 2011
Grant date	Apr 22, 2014
Priority date	—
Expiry date	Mar 17, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Provided is a method of obtaining biologically active recombinant human G-CSF from inclusion bodies, wherein the solubilization and refolding process can be performed at ambient temperature and the purification step comprises reversed phase chromatography (RP), in particular RP-HPLC. The G-CSF preparation so obtained is characterized by high purity and homogeneity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.