Patent · US Active

Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers

US8703196B2 · kind B2 · utility

40Cited by

5References

15Claims

0Family size

Assignee

Bend Reserch, Inc. · US

Inventors

Walter C. Babcock · Bend, US
William J. Curatolo · Niantic, US
Dwayne T. Friesen · Bend, US
Rodney James Ketner · Bend, US
Julian B. Lo · Old Lyme, US
James A. S. Nightingale · Bend, US
Ravi M. Shanker · Groton, US
James B. West · Bend, US

Key dates

Filing date	Jul 31, 2012
Grant date	Apr 22, 2014
Priority date	—
Expiry date	Jul 31, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A pharmaceutical composition comprises a dispersion comprising a low-solubility drug and a matrix combined with a concentration-enhancing polymer. At least a major portion of the drug is amorphous in the dispersion. The compositions improve the stability of the drug in the dispersion, and/or the concentration of drug in a use environment.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.