Pichia pastoris deficient in endogenous secreted protease
US8703444B2 · kind B2 · utility
0Cited by
1References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 13, 2010 |
| Grant date | Apr 22, 2014 |
| Priority date | — |
| Expiry date | Dec 13, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P21/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to micro-organisms and to methods of producing proteins. More specifically, the inventions relates to a host cell useful for the expression of heterozygous proteins in which the host cell, Pichia pastoris, has been genetically modified so that the gene for endogenous secreted subtilisin Sub2 protease is completely or partially inactivated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.