Method for the production of free carboxylic acids

US8703451B2 · kind B2 · utility

Assignee

• Evonik Röhm GmbH · DE

Inventors

• Thomas Haas · Munster, DE
• Thomas Tacke · Friedrichsdorf, DE
• Achim Marx · Bielefeld, DE
• Alexander Schraven · Issum, DE
• Olivier Zehnacker · Dortmund, DE
• Eva Maria Wittmann · Traunreut, DE

Key dates

• Filing date: Apr 29, 2009
• Grant date: Apr 22, 2014
• Expiry date: Dec 4, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C51/47
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of free carboxylic acids including: A) preparation of carboxylic acid by a biological cell located in an aqueous medium with addition of an amine of formula (I)where R1, R2 and R3, independently of one another, are identical or different, branched or unbranched, optionally substituted hydrocarbon radicals or H; B) for cases where the added amine A) is water-soluble, addition of a water-insoluble amine of formula (I), where, in A) or B), a multiphase system is obtained and the corresponding ammonium carboxylate is formed from the water-insoluble amine and the carboxylic acid; C) removal of the water-insoluble phase; and D) heating of the water-insoluble phase with release of free carboxylic acid.