Four branched dendrimer-PEG for conjugation to proteins and peptides
US8703893B2 · kind B2 · utility
12Cited by
2References
2Claims
0Family size
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Key dates
| Filing date | Nov 20, 2006 |
| Grant date | Apr 22, 2014 |
| Priority date | — |
| Expiry date | Aug 4, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A polymeric dendrimer-like structure with four branches of monomethoxy-polyethylene glycol that can be represented as:The carboxylic group of the previous structure can be functionalized for the production of conjugates of pharmaceutical interest. The binding of this dendrimer-like polyethylene glycol to therapeutic proteins improves their in vitro and in vivo stability.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.