Method for preparing rosuvastatin calcium intermediate
US8703944B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Feb 3, 2013 |
| Grant date | Apr 22, 2014 |
| Priority date | — |
| Expiry date | Feb 3, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for preparing a rosuvastatin calcium intermediate represented by formula I. The method includes: hydrolyzing an ester compound represented by formula II (in which, R represents C1-C5) in the presence of a metal compound to obtain a carboxylic acid compound represented by formula III; and reducing the carboxylic acid compound in the presence of a reductant.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.