Methods and kits for volumetric distribution of pharmaceutical agents via the vascular adventitia and microcirculation
US8708995B2 · kind B2 · utility
84Cited by
24References
22Claims
0Family size
Assignee
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Key dates
| Filing date | May 28, 2010 |
| Grant date | Apr 29, 2014 |
| Priority date | — |
| Expiry date | May 31, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2025/1086
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods and kits for delivering pharmaceutical agents to the adventitia and other regions outside the external elastic lamina (EEL) surrounding a blood vessel utilize a catheter having a needle. The needle is positioned in up to 5 mm beyond the EEL and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood vessel and, in many cases, extend longitudinally and radially along the blood vessel. Confirmation that a delivery aperture of the needle lies beyond the EEL may be required before delivering the pharmaceutical agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.