Cationic polymers for antimicrobial applications and delivery of bioactive materials
US8709466B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 21, 2011 |
| Grant date | Apr 29, 2014 |
| Priority date | — |
| Expiry date | Dec 21, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/88
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A cationic star polymer is disclosed of the general formula (1):I′P′]w′ (1),wherein w′ is a positive number greater than or equal to 3, I′ is a dendritic polyester core covalently linked to w′ independent peripheral linear cationic polymer chains P′. Each of the chains P′ comprises a cationic repeat unit comprising i) a backbone functional group selected from the group consisting of aliphatic carbonates, aliphatic esters, aliphatic carbamates, aliphatic ureas, aliphatic thiocarbamates, aliphatic dithiocarbonates, and combinations thereof, and ii) a side chain comprising a quaternary amine group. The quaternary amine group comprises a divalent methylene group directly covalently linked to i) a positive charged nitrogen and ii) an aromatic ring.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.